Supramolecular nanosolventbased hollow fiber liquid phase. Kinetic aspects of hollow fiber liquid phase microextraction and electromembrane extraction. Ionic liquidbased hollow fibersupported liquidphase. Sdme in its original form, first described by jeannot and cantwell in 1996 24, is the simplest way to perform lpme. Some important extraction parameters, such as effect of salt. Development of hollowfiber liquidphase microextraction method.
Application of hollow fiber liquid phase microextraction and dispersive liquid liquid microextraction techniques in analytical toxicology. Handbook of solid phase microextraction pdf converter. Application of hollow fiber liquid phase microextraction. Hollow fiber liquidphase microextraction hflpme liquidphase microextraction lpme miniaturization. Cabergoline was extracted from 15 ml of basic sample solution with ph of 10 into an organic extracting solvent noctanol impregnated in the. Liquidphase microextraction an overview sciencedirect. Comparison of hollow fiber liquid phase microextraction.
Hollow fiber supported liquidphase microextraction. Determination of triazole fungicides using hollow fiber. Development of hollowfiber liquidphase microextraction. A new method for the determination of four endocrine disrupting compounds edcs bisphenol a, 17. Liquidliquid extraction lle is a popular method for separation of. A new hollow fiber liquidsolid phase microextraction. Hidalgo, evaluation of a tertiary system peracetic aciduv radiation for the removal of selected. Continued ils pretreatment methods contaminants sample ref. Hollow fiber liquid phase microextraction followed by high performance liquid chromatography for determination of ultratrace levels of seiv after derivatization in urine. Both methodologies, that is, static lpme with hf and dynamic lpme with hf, involved the use of a small volume of organic solvent impregnated in the hollow fiber, which was held by the needle of a. Hollow fiber liquid phase microextraction method based on a new deep eutectic solvent for extraction and derivatization of some phenolic compounds in beverage samples packed in plastics. Comparison of hollow fiber liquid phase microextraction and ultrasoundassisted lowdensity solvent dispersive liquid liquid microextraction for the determination of drugs of abuse in biological samples by gas chromatographymass spectrometry. Hollow fiberprotected liquidphase microextraction of.
A new microextraction technique termed hollow fiber protected liquid phase microextraction lpme was developed. These methods use microvolume solvent and illustrate the simpler, faster, and more inexpensive than traditional liquid extraction. Application of hollow fiber liquid phase microextraction for. Hollow fiber liquid phase microextraction followed by gas chromatography flame ionization detection for the determination of amitraz in honey and water samples author. Liquidphase microextraction combined with hollow fiber as a. Hollowfibersupported liquidphase microextraction using. Abstracta method of ionic liquid based hollow fiber liquidphase microextraction enhanced electrically was successfully developed and applied to the extraction and determination of neutral red nr dye, which was selected as the model analyte. Hollow fiber liquidphase microextraction hflpme technique has been shown to be a reliable and valid in measuring trace amount of different. Twostep hollow fiber based, liquid phase microextraction combined with highperformance liquid chromatography. Capillary electrophoresis and hollow fiber liquid phase microextraction for the enantioselective determination of albendazole sulfoxide after biotransformation of albendazole by an endophytic fungus.
Both methods allow the direct transfer of extracted analytes to a gcms system for analysis. Application of hollow fiber assisted liquidphase microextraction to identify avermectins in stream water using msms. Automated on line liquid liquid extraction system for temporal mass spectrometric analysis of dynamic samples. Hollow fiberbased liquid phase microextraction followed by analytical instrumental techniques for quantitative analysis of heavy metal ions and. Pdf developments in hollow fiber based liquidphase. Hollow fiberbased liquid phase microextraction followed by. In this paper, a three phase hollow fiber based liquid phase microextraction hflpme combined with a hplc procedure using diode array dad and fluorescence detection fld has been developed for the determination of eight widely used fluoroquinolones. Lpme method was established for purification and enrichment of glutathione gsh in human saliva followed by a miniaturized capillary electrophoresis with amperometric detection system mini. Hollow fiber liquid phase microextraction followed by high performance liquid chromatography for determination of ultratrace levels of seiv after derivatization in urine, plasma and natural water samples. This paper presents a new method for quantitative analysis of methamphetamine map in urine samples based on hollow fiber based solid liquid phase microextraction hfslpme in combination with theta capillaryelectrospray ionization mass spectrometry tcesims detection. In this method the porous polypropylene hollow fibers filled with a few microliters of organic solvent, were immersed in aqueous sam. In this study, for the first time, coextraction of acidic, basic and amphiprotic pollutants was performed using supramolecular nanosolventbased hollow fiber liquid phase microextraction sshflpme as an efficient method followed by high performance liquid chromatographyphotodiode array detection.
We report the application of the dispersive liquid liquid microextraction coupled to hollow fibre membraneassisted liquid phase microextraction and its application for extraction of atrazine and triclosan. A method termed hollow fiber liquid phase microextraction hflpme was utilized to extract three chlo rophenols, 2chlorophenol 2cp, 2,4dichlorophenol 2,4dcp and 2,4,6trichlorophenol 2,4,6tcp, separately from water. Singledrop microextraction sdme recommended articles citing articles 0 view full text. Hollow fiberliquid phase microextraction method based on. Comparison of hollow fiber liquid phase microextraction and dispersive liquid liquid microextraction for the determination of organosulfur pesticides in environmental and beverage samples by gas chromatography with flame photometric detection. Hollow fiber liquidphase microextraction hflpme is one of the lpme methods. For the analysis of polar or ionizable analytes, a three phase system is frequently used with an organic solvent immobilized in the hollow fiber. It is also cheap as the fiber can be disposed once used, thus minimizing carry over problems. Threephase hollow fiber liquidphase microextraction and. Analytical and bioanalytical chemistry 2011, 399 6.
Features include high selectivity, good enrichment factors, and improved possibilities for automation. Hollow fiberbased liquid phase microextraction hflpme. Applications of liquidphase microextraction in the sample. Triazines were employed as model compounds to assess the extraction procedure and were determined by gas chromatographymass spectrometry. The slm principle was applied to liquid phase microextraction for the first time by introducing hollow fiber liquid phase microextraction hflpme in 1999. Toluene functioned as both the extraction solvent and the impregnation solvent. Hollow fiber liquidphase microextraction request pdf. Applications of these newly emerging developments in extraction and preconcentration of a vast category of compounds including heavy metals, pesticides, pharmaceuticals and abused drugs in complex matrices.
Pdf application of hollowfiberassisted liquidphase. Most real samples cannot directly be infused to mass spectrometers because they could contaminate delicate. Injection port derivatization following ionpair hollow. Hollow fiber liquid phase microextraction hflpme exhibits many advantages compared to the other microextraction techniques in terms of simplicity and minimum consumption of organic solvents. The applicability of hollow fiber liquid phase microextraction hflpme combined with highperformance liquid chromatographyultraviolet detection hplcuv was evaluated for the extraction and determination of tamoxifen tam in biological fluids including human urine and plasma. Trace determination of tamoxifen in biological fluids. Environmental application, fate, effects and concerns of. The extracted chlorophenols were then separated, identified, and quantified by. Figure schematic diagram of threephase hflpme based of two immiscible. For the first time, hollowfiber liquidphase microextraction combined with highperformance liquid chromatographyultraviolet was used to extract trans,transmuconic acid, in urine samples of workers who had been exposed to benzene. Is anyone using hflpme, hollow fiber liquid phase microextraction. Hollowfiber microporous membrane liquidliquid extraction. Hplpme relies on the extraction of target analytes from aqueous samples into a supported liquid membrane slm sustained in the pores of.
In this study, a simple and efficient hollow fiber liquid phase microextraction hflpme method coupled with high performance liquid chromatography has been developed for preconcentration and determination of cabergoline in plasma and urine samples. Hollow fiber based liquid phase microextraction technique hflpme was proposed in 1999 as an efficient alternative to the conventional sample preparation methods. Extraction of cuii ions in wastewaters using new solid. For this reason a twophase hollow fiber liquid phase microextraction method for the. Pdf hollow fiber liquid phase microextraction followed. Electromembrane extraction, or eme, is a miniaturized liquid liquid extraction technique developed for sample preparation of aqueous samples prior to analysis by chromatography, electrophoresis, mass spectrometry, and related techniques in analytical chemistry. The principles of hflpme are presented with focus on both two and threephase extractions. Pdf hollow fiber liquidphase microextraction hflpme offers an efficient.
Basic principles and applications of liquid phase microextraction techniques nerin c scientia chromatographica 2016. Hollow fiber liquidphase microextraction hflpme is commonly used to minimize consumption of organic solvent for extraction and to protect the extraction phase from contamination or depletion 110. Eme involves the use of a small supported liquid membrane slm sustained in the wall of a porous hollow fiber, and application of an. A simple and highly sensitive method that involves three phase hollow fiber supported liquid phase microextraction hflpme coupled with maltodextrin mdmodified capillary electrophoresis ce was successfully developed for the separation and determination of trace concentrations of citalopram cit enantiomers in urine samples. A two phase hollow fiber liquid phase microextraction hflpme and gas chromatography mass spectrometry gcms method for the separation and determination of triazole fungicides, namely, penconazole, hexaconazole, diclobutrazole and diniconazole, is described. The principles of three liquid phase microextraction methods including singledrop microextraction, dispersive liquid liquid microextraction and hollow fiber microextraction have been described.
If so, let me know the supplier of the fibers, the compounds you have been extracting and your perception of the method. The enhancement technique involved dispersing al 2 o 3 particles in nbutanol to fill the pores and lumen of a polyether sulfone membrane fiber. A new hollow fiberliquidsolid phase microextraction for extraction of ginsenosides from a chinese compound formula was established using al 2 o 3 nanoparticles as the adsorbent. Pdf basic principles and applications of liquid phase. Two modes of liquid phase microextraction lpme combined with hollow fiber hf were developed for gas chromatographymass spectrometry gcms. Hollow fiberbased solidliquid phase microextraction. Liquidphase microextraction combined with hollow fiber as. For the first time, hollowfiber liquidphase microextraction combined with highperformance liquid chromatographyultraviolet was used to extract. Recently, hollow fiber liquid phase micro extraction hflpme, based on the application of a supported liquid membrane, was introduced using a porous. It starts with an introduction to the method and its subclasses and further develops into three distinct sections of single.
Application of hollow fiber liquid phase microextraction and. The extraction conditions were optimized for the four triazole fungicides as follows. Pdf capillary electrophoresis and hollow fiber liquid. The drug was extracted from a 15 ml aqueous sample source phase. Yamini, yadollah, faraji, mohammad, ghambarian, mahnaz source. The application of microextraction for the determination of drugs in biological samples 3 febri annuryanti 10145222 liquid phase microextraction lpme 2.
Application of hollow fiber liquid phase microextraction and dispersive liquidliquid microextraction techniques in analytical toxicology. Applications of these newly emerging developments in extraction. Qi decoction and the single herb, fructus aurantii immaturus, cortex magnoliae. Request pdf hollow fiber liquidphase microextraction this chapter discusses hollow fiber liquidphase microextraction lpme. C 8 mimpf 6 ultrasonic assisted dispersive liquid liquid microextraction fluoroquinolones water 19 c 8 mimpf 6 ultrasonic assisted dispersive liquid liquid microextraction pyrethroid pesticides honey 20 c 6 mimfap dispersive liquid liquid microextractionwithmicro solid phase extraction antidepressant drugs water 21. Comparison of hollow fiber liquidphase microextraction. Hollow fiber liquidphase microextraction hflpme offers an efficient alternative to classical techniques for sample preparation and preconcentration. Liquid phase microextraction or solvent microextraction was developed as a fast, simple and inexpensive solventminimized liquid liquid extraction lle technique 8 9. The chapter comprises a short discussion of the basic setup and. The use of porous hollow fibers as the slm was a new approach combining the benefits of small volumes and high enrichment factors in sdme with the robustness and selectivity obtained with the slm technique. The three main approaches to lpme are single drop microextraction sdme, hollow fiber liquid phase microextraction hflpme and dispersive liquid liquid microextraction dllme. Comparison of solid phase microextraction and hollow fiber liquid phase microextraction for the determination of pesticides in aqueous samples by gas chromatography triple quadrupole tandem mass spectrometry. A two phase hollow fiber hf liquid phase microextraction lpme method followed by gas chromatography was developed for quantification of 8 major polybrominated diphenyl ethers at trace level in sewage sludge.
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